› 1fzq

X-ray diffraction
1.7Å resolution

CRYSTAL STRUCTURE OF MURINE ARL3-GDP

Released:
DOI: 10.2210/pdb1fzq/pdb
PDB entry 1fzq coloured by chain, front view.
PDB entry 1fzq coloured by chain, side view.
PDB entry 1fzq coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structural and biochemical properties show ARL3-GDP as a distinct GTP binding protein.
Hillig RC, Hanzal-Bayer M, Linari M, Becker J, Wittinghofer A, Renault L
Structure 8 1239-45 (2000)
PMID: 11188688

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194392 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ADP-ribosylation factor-like protein 3 Chain: A
Molecule details ›
Chain: A
Length: 181 amino acids
Theoretical weight: 20.38 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9WUL7 (Residues: 2-182; Coverage: 100%)
Gene name: Arl3
Sequence domains: ADP-ribosylation factor family
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

4 bound ligands:
Ligand SO4 2 x SO4
Ligand NH4 1 x NH4
Ligand MES 1 x MES
Ligand GDP 1 x GDP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID13
Spacegroup: P21212
Unit cell:
a: 74.421Å b: 64.583Å c: 40.386Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.215 0.213 0.235
Expression system: Escherichia coli

Quick links

Citations

7 review citations

Structure-function relationships of the G domain, a canonical switch motif.
Wittinghofer et al. (2011)
6 more

9 mentions without citation

Fast and accurate multivariate Gaussian modeling of protein families: predicting residue contacts and protein-interaction partners.
Baldassi et al. (2014)
8 more