› 1g4r

X-ray diffraction
2.2Å resolution

CRYSTAL STRUCTURE OF BOVINE BETA-ARRESTIN 1

Released:
DOI: 10.2210/pdb1g4r/pdb
PDB entry 1g4r coloured by chain, front view.
PDB entry 1g4r coloured by chain, side view.
PDB entry 1g4r coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Crystal structure of beta-arrestin at 1.9 A: possible mechanism of receptor binding and membrane Translocation.
Han M, Gurevich VV, Vishnivetskiy SA, Sigler PB, Schubert C
Structure 9 869-80 (2001)
PMID: 11566136

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148193 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Beta-arrestin-1 Chain: A
Molecule details ›
Chain: A
Length: 393 amino acids
Theoretical weight: 44.31 KDa
Source organism: Bos taurus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P17870 (Residues: 1-393; Coverage: 94%)
Gene name: ARRB1
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: P3221
Unit cell:
a: 77.806Å b: 77.806Å c: 157.099Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.262 0.238 0.274
Expression system: Escherichia coli BL21

Quick links

Citations

64 review citations

Beta-arrestins and cell signaling.
DeWire et al. (2007)
63 more

23 mentions without citation

Discovery of new GPCR biology: one receptor structure at a time.
Hanson et al. (2009)
22 more