Function and Biology Details
Reaction catalysed:
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- Type III secreted modular tyrosine phosphatase, SptP/YopH
- Tyrosine-specific protein phosphatase, PTPase domain
- Protein-tyrosine phosphatase-like
- Virulence factor YopE, GAP domain
- Virulence factor YopE, GAP domain superfamily
- Protein-tyrosine phosphatase, active site
- Tyrosine-specific protein phosphatases domain
- Protein-tyrosine phosphatase, catalytic
Structure domains:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Secreted effector protein SptP (preferred)
PDBe Complex ID:
PDB-CPX-159955 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Secreted effector protein SptP
Molecule details ›
Chain: R
Length: 383 amino acids
Theoretical weight: 42.13 KDa
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium
Expression system: Escherichia coli BL21
UniProt:
Sequence domains:
Structure domains:
Length: 383 amino acids
Theoretical weight: 42.13 KDa
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
P74873 (Residues: 161-543; Coverage: 71%)
Sequence domains:
Structure domains:
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
RIGAKU RU200
Spacegroup:
I222
Expression system: Escherichia coli BL21
