› 1g6q

X-ray diffraction
2.9Å resolution

CRYSTAL STRUCTURE OF YEAST ARGININE METHYLTRANSFERASE, HMT1

Released:
DOI: 10.2210/pdb1g6q/pdb
PDB entry 1g6q coloured by chain, front view.
PDB entry 1g6q coloured by chain, side view.
PDB entry 1g6q coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
The structure and oligomerization of the yeast arginine methyltransferase, Hmt1.
Weiss VH, McBride AE, Soriano MA, Filman DJ, Silver PA, Hogle JM
Nat Struct Biol 7 1165-71 (2000)
PMID: 11101900

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
homo hexamer
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-153538 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein arginine N-methyltransferase 1 Chains: 1, 2, 3, 4, 5, 6
Molecule details ›
Chains: 1, 2, 3, 4, 5, 6
Length: 328 amino acids
Theoretical weight: 37.69 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P38074 (Residues: 21-348; Coverage: 94%)
Gene names: HMT1, ODP1, RMT1, YBR0320, YBR034C
Sequence domains: Ribosomal protein L11 methyltransferase (PrmA)
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12C
Spacegroup: P21
Unit cell:
a: 84.1Å b: 129.43Å c: 101.43Å
α: 90° β: 102.74° γ: 90°
R-values:
R R work R free
0.253 0.253 0.294
Expression system: Escherichia coli

Quick links

Citations

16 review citations

Structural and sequence motifs of protein (histone) methylation enzymes.
Cheng et al. (2005)
15 more

3 mentions without citation

AdoMet-dependent methylation, DNA methyltransferases and base flipping.
Cheng et al. (2001)
2 more