1g6r

X-ray diffraction
2.8Å resolution

A FUNCTIONAL HOT SPOT FOR ANTIGEN RECOGNITION IN A SUPERAGONIST TCR/MHC COMPLEX

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-134585 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
T-cell receptor alpha chain V region PHDS58 Chains: A, C
Molecule details ›
Chains: A, C
Length: 202 amino acids
Theoretical weight: 22.3 KDa
Source organism: Mus musculus
Expression system: Drosophila melanogaster
UniProt:
  • Canonical: P01738 (Residues: 21-130; Coverage: 100%)
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins
T-cell receptor beta-1 chain C region Chains: B, D
Molecule details ›
Chains: B, D
Length: 237 amino acids
Theoretical weight: 26.28 KDa
Source organism: Mus musculus
Expression system: Drosophila melanogaster
UniProt:
  • Canonical: P01852 (Residues: 1-127; Coverage: 73%)
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
H-2 class I histocompatibility antigen, K-B alpha chain Chains: H, I
Molecule details ›
Chains: H, I
Length: 274 amino acids
Theoretical weight: 31.65 KDa
Source organism: Mus musculus
Expression system: Drosophila melanogaster
UniProt:
  • Canonical: P01901 (Residues: 22-295; Coverage: 79%)
Gene names: H2-K, H2-K1
Sequence domains:
Structure domains:
Beta-2-microglobulin Chains: L, M
Molecule details ›
Chains: L, M
Length: 99 amino acids
Theoretical weight: 11.7 KDa
Source organism: Mus musculus
Expression system: Drosophila melanogaster
UniProt:
  • Canonical: P01887 (Residues: 21-119; Coverage: 100%)
Gene name: B2m
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
SIYR PEPTIDE Chains: P, Q
Molecule details ›
Chains: P, Q
Length: 8 amino acids
Theoretical weight: 1.04 KDa

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-1
Spacegroup: P21212
Unit cell:
a: 297.71Å b: 94.57Å c: 84.89Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.298 0.298 0.327
Expression system: Drosophila melanogaster