› 1g86

X-ray diffraction
1.8Å resolution

Function and Biology Details

Reaction catalysed: 
2-lysophosphatidylcholine + H(2)O = glycerophosphocholine + a carboxylate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170167 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Galectin-10 Chain: A
Molecule details ›
Chain: A
Length: 142 amino acids
Theoretical weight: 16.5 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q05315 (Residues: 1-142; Coverage: 100%)
Gene names: CLC, LGALS10, LGALS10A
Sequence domains: Galactoside-binding lectin
Structure domains: Jelly Rolls

Ligands and Environments

1 bound ligand:
Ligand NEQ 2 x NEQ
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX9.6, RIGAKU RU300
Spacegroup: P6522
Unit cell:
a: 49.71Å b: 49.71Å c: 264.86Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.203 0.203 0.242

Quick links

Citations

26 review citations

Eosinophils: biological properties and role in health and disease.
Hogan et al. (2008)
25 more

3 mentions without citation

Cloning, expression, purification and crystallographic studies of galectin-11 from domestic sheep (Ovis aries).
Sakthivel et al. (2015)
2 more