› 1g9u

X-ray diffraction
2.35Å resolution

CRYSTAL STRUCTURE OF YOPM-LEUCINE RICH EFFECTOR PROTEIN FROM YERSINIA PESTIS

Released:
DOI: 10.2210/pdb1g9u/pdb
PDB entry 1g9u coloured by chain, front view.
PDB entry 1g9u coloured by chain, side view.
PDB entry 1g9u coloured by chain, top view.
Source organism: Yersinia pestis
Primary publication:
Unusual molecular architecture of the Yersinia pestis cytotoxin YopM: a leucine-rich repeat protein with the shortest repeating unit.
Evdokimov AG, Anderson DE, Routzahn KM, Waugh DS
J Mol Biol 312 807-21 (2001)
PMID: 11575934

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148169 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Outer membrane protein YopM Chain: A
Molecule details ›
Chain: A
Length: 454 amino acids
Theoretical weight: 51.59 KDa
Source organism: Yersinia pestis
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P17778 (Residues: 1-386, 387-409; Coverage: 100%)
Gene names: YPCD1.26c, YP_pCD60, y0059, y5054, yop48, yopM
Sequence domains:
Structure domains: Ribonuclease Inhibitor

Ligands and Environments

3 bound ligands:
Ligand ACT 9 x ACT
Ligand CA 2 x CA
Ligand HG 8 x HG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X9B
Spacegroup: P4222
Unit cell:
a: 109.359Å b: 109.359Å c: 101.499Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.21 0.2 0.23
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

30 review citations

Yersinia outer proteins: role in modulation of host cell signaling responses and pathogenesis.
Viboud et al. (2005)
29 more

10 mentions without citation

Ribonuclease inhibitor: structure and function.
Dickson et al. (2005)
9 more