› 1gcm

X-ray diffraction
1.8Å resolution

GCN4 LEUCINE ZIPPER CORE MUTANT P-LI

Released:
DOI: 10.2210/pdb1gcm/pdb
PDB entry 1gcm coloured by chain, front view.
PDB entry 1gcm coloured by chain, side view.
PDB entry 1gcm coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Crystal structure of an isoleucine-zipper trimer.
Harbury PB, Kim PS, Alber T
Nature 371 80-3 (1994)
PMID: 8072533

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136531 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
General control transcription factor GCN4 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 34 amino acids
Theoretical weight: 4.07 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Not provided
UniProt:
  • Canonical: P03069 (Residues: 249-281; Coverage: 12%)
Gene names: AAS101, AAS3, ARG9, GCN4, YEL009C
Sequence domains: Basic region leucine zipper

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P21
Unit cell:
a: 35.32Å b: 39.67Å c: 36.97Å
α: 90° β: 98.38° γ: 90°
R-values:
R R work R free
0.175 not available not available
Expression system: Not provided

Quick links

Citations

32 review citations

De novo design and structural characterization of proteins and metalloproteins.
DeGrado et al. (1999)
31 more

15 mentions without citation

De novo protein design, a retrospective.
Korendovych et al. (2020)
14 more