› 1ggq

X-ray diffraction
2.51Å resolution

OUTER SURFACE PROTEIN C (OSPC) OF BORRELIA BURGDORFERI STRAIN B31

Released:
DOI: 10.2210/pdb1ggq/pdb
PDB entry 1ggq coloured by chain, front view.
PDB entry 1ggq coloured by chain, side view.
PDB entry 1ggq coloured by chain, top view.
Source organism: Borreliella burgdorferi B31
Primary publication:
Crystal structure of outer surface protein C (OspC) from the Lyme disease spirochete, Borrelia burgdorferi.
Kumaran D, Eswaramoorthy S, Luft BJ, Koide S, Dunn JJ, Lawson CL, Swaminathan S
EMBO J 20 971-8 (2001)
PMID: 11230121

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-170455 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Outer surface protein C Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 174 amino acids
Theoretical weight: 18.6 KDa
Source organism: Borreliella burgdorferi B31
Expression system: Escherichia coli
UniProt:
  • Canonical: Q07337 (Residues: 37-210; Coverage: 91%)
Gene names: BB_B19, ospC
Sequence domains: Lipoprotein
Structure domains: Lipoprotein, type 6

Ligands and Environments

1 bound ligand:
Ligand MG 1 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12C
Spacegroup: P1
Unit cell:
a: 127.206Å b: 33.654Å c: 47.993Å
α: 84.04° β: 81.55° γ: 89.23°
R-values:
R R work R free
0.235 0.231 0.265
Expression system: Escherichia coli

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Citations

10 review citations

The burgeoning molecular genetics of the Lyme disease spirochaete.
Rosa et al. (2005)
9 more

14 mentions without citation

Complement Evasion by Lyme Disease Spirochetes.
Skare et al. (2020)
13 more