› 1gje

Solution NMR

Peptide Antagonist of IGFBP-1, Minimized Average Structure

Released:
DOI: 10.2210/pdb1gje/pdb
PDB entry 1gje coloured by chain, front view.
PDB entry 1gje coloured by chain, side view.
PDB entry 1gje coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Structure-function analysis of a phage display-derived peptide that binds to insulin-like growth factor binding protein 1.
Skelton NJ, Chen YM, Dubree N, Quan C, Jackson DY, Cochran A, Zobel K, Deshayes K, Baca M, Pisabarro MT, Lowman HB
Biochemistry 40 8487-98 (2001)
PMID: 11456486

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-162197 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
IGFBP-1 antagonist Chain: A
Molecule details ›
Chain: A
Length: 16 amino acids
Theoretical weight: 1.77 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: restrained molecular dynamics
Expression system: Not provided

Quick links

Citations

8 review citations

Unraveling hot spots in binding interfaces: progress and challenges.
DeLano WL. (2002)
7 more

1 mention without citation

Generalized pattern search algorithm for Peptide structure prediction.
Nicosia et al. (2008)