› 1gjj

Solution NMR

N-TERMINAL CONSTANT REGION OF THE NUCLEAR ENVELOPE PROTEIN LAP2

Released:
DOI: 10.2210/pdb1gjj/pdb
PDB entry 1gjj coloured by chain, front view.
PDB entry 1gjj coloured by chain, side view.
PDB entry 1gjj coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of the constant region of nuclear envelope protein LAP2 reveals two LEM-domain structures: one binds BAF and the other binds DNA.
Cai M, Huang Y, Ghirlando R, Wilson KL, Craigie R, Clore GM
EMBO J 20 4399-407 (2001)
PMID: 11500367

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-154500 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lamina-associated polypeptide 2, isoform alpha Chain: A
Molecule details ›
Chain: A
Length: 168 amino acids
Theoretical weight: 18.41 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P42166 (Residues: 1-168; Coverage: 24%)
Gene names: LAP2, TMPO
Sequence domains:
Structure domains: Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: RESTRAINED SIMULATED IN TORSION ANGLE SPACE
Expression system: Escherichia coli

Quick links

Citations

53 review citations

Lamins: nuclear intermediate filament proteins with fundamental functions in nuclear mechanics and genome regulation.
Gruenbaum et al. (2015)
52 more

2 mentions without citation

MolProbity for the masses-of data.
Chen et al. (2015)
1 more