› 1gna

Solution NMR

DETERMINATION OF THE SOLUTION STRUCTURE OF THE PEPTIDE HORMONE GUANYLIN: OBSERVATION OF A NOVEL FORM OF TOPOLOGICAL STEREOISOMERISM

Released:
DOI: 10.2210/pdb1gna/pdb
PDB entry 1gna coloured by chain, ensemble of 20 models, front view.
PDB entry 1gna coloured by chain, ensemble of 20 models, side view.
PDB entry 1gna coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Determination of the solution structure of the peptide hormone guanylin: observation of a novel form of topological stereoisomerism.
Skelton NJ, Garcia KC, Goeddel DV, Quan C, Burnier JP
Biochemistry 33 13581-92 (1994)
PMID: 7947768

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-169743 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Guanylin Chain: A
Molecule details ›
Chain: A
Length: 13 amino acids
Theoretical weight: 1.31 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q02747 (Residues: 103-115; Coverage: 14%)
Gene names: GUCA2, GUCA2A

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Not provided

Quick links

Citations

7 review citations

Occurrence, distribution, and associations of O and H serogroups, colonization factor antigens, and toxins of enterotoxigenic Escherichia coli.
Wolf MK. (1997)
6 more

6 mentions without citation

Enterotoxigenic Escherichia coli: intestinal pathogenesis mechanisms and colonization resistance by gut microbiota.
Zhang et al. (2022)
5 more