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Solution NMR

SOLUTION STRUCTURE OF THE N-TERMINAL ZINC FINGER OF MURINE GATA-1, NMR, 25 STRUCTURES

Released:
DOI: 10.2210/pdb1gnf/pdb
PDB entry 1gnf coloured by chain, ensemble of 25 models, front view.
PDB entry 1gnf coloured by chain, ensemble of 25 models, side view.
PDB entry 1gnf coloured by chain, ensemble of 25 models, top view.
Source organism: Mus musculus
Primary publication:
The solution structure of the N-terminal zinc finger of GATA-1 reveals a specific binding face for the transcriptional co-factor FOG.
Kowalski K, Czolij R, King GF, Crossley M, Mackay JP
J Biomol NMR 13 249-62 (1999)
PMID: 10212985

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148126 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Erythroid transcription factor Chain: A
Molecule details ›
Chain: A
Length: 46 amino acids
Theoretical weight: 5.2 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P17679 (Residues: 200-243; Coverage: 11%)
Gene names: Gata1, Gf-1
Sequence domains: GATA zinc finger
Structure domains: Erythroid Transcription Factor GATA-1, subunit A

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DISTANCE GEOMETRY, SIMULATED ANNEALING
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

Zinc finger proteins: new insights into structural and functional diversity.
Laity et al. (2001)
1 more

7 mentions without citation

Structural classification of zinc fingers: survey and summary.
Krishna et al. (2003)
6 more