› 1gv6

Solution NMR

Solution structure of alfa-L-LNA:DNA duplex

Released:
DOI: 10.2210/pdb1gv6/pdb
PDB entry 1gv6 coloured by chain, ensemble of 20 models, front view.
PDB entry 1gv6 coloured by chain, ensemble of 20 models, side view.
PDB entry 1gv6 coloured by chain, ensemble of 20 models, top view.
Source organism: Synthetic construct
Primary publication:
alpha-L-LNA (alpha-L-ribo configured locked nucleic acid) recognition of DNA: an NMR spectroscopic study.
Nielsen KM, Petersen M, Håkansson AE, Wengel J, Jacobsen JP
Chemistry 8 3001-9 (2002)
PMID: 12489231

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-113069 (preferred)
Entry contents:
1 distinct DNA molecule
1 distinct DNA/RNA hybrid molecule
Macromolecules (2 distinct):
5- D(*GP*CP*AP*GP*AP*AP*GP*CP*AP*G) -3 Chain: B
Molecule details ›
Chain: B
Length: 10 nucleotides
Theoretical weight: 3.1 KDa
Source organism: Synthetic construct
Expression system: Not provided
5- D(*CP*(ATL)P*GP*CP*(ATL)P*(ATL)P*CP*(ATL)P* GP*C) -3 Chain: A
Molecule details ›
Chain: A
Length: 10 nucleotides
Theoretical weight: 3.1 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
1 modified residue:
Ligand ATL 4 x ATL

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Not provided

Quick links

Citations

3 review citations

Pyrene-functionalized oligonucleotides and locked nucleic acids (LNAs): tools for fundamental research, diagnostics, and nanotechnology.
Østergaard et al. (2011)
2 more