› 1gyf

Solution NMR

GYF DOMAIN FROM HUMAN CD2BP2 PROTEIN

Released:
DOI: 10.2210/pdb1gyf/pdb
PDB entry 1gyf coloured by chain, ensemble of 16 models, front view.
PDB entry 1gyf coloured by chain, ensemble of 16 models, side view.
PDB entry 1gyf coloured by chain, ensemble of 16 models, top view.
Source organism: Homo sapiens
Primary publication:
The GYF domain is a novel structural fold that is involved in lymphoid signaling through proline-rich sequences.
Freund C, Dötsch V, Nishizawa K, Reinherz EL, Wagner G
Nat Struct Biol 6 656-60 (1999)
PMID: 10404223

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131918 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CD2 antigen cytoplasmic tail-binding protein 2 Chain: A
Molecule details ›
Chain: A
Length: 62 amino acids
Theoretical weight: 7.32 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O95400 (Residues: 280-341; Coverage: 18%)
Gene names: CD2BP2, KIAA1178
Sequence domains: GYF domain
Structure domains: Dna Ligase; domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

11 review citations

The importance of being proline: the interaction of proline-rich motifs in signaling proteins with their cognate domains.
Kay et al. (2000)
10 more

2 mentions without citation

Overview of protein structural and functional folds.
Sun et al. (2004)
1 more