Function and Biology Details
Reactions catalysed:
(R)-3-hydroxyacyl-CoA + NAD(+) = 3-oxoacyl-CoA + NADH
(24R,25R)-3-alpha,7-alpha,12-alpha,24-tetrahydroxy-5-beta-cholestanoyl-CoA = (24E)-3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA + H(2)O
(3R)-3-hydroxyacyl-CoA = (2E)-2-enoyl-CoA + H(2)O
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
(3R)-hydroxyacyl-CoA dehydrogenase (preferred)
PDBe Complex ID:
PDB-CPX-161334 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
(3R)-hydroxyacyl-CoA dehydrogenase
Molecule details ›
Chains: A, B, C, D
Length: 319 amino acids
Theoretical weight: 34.82 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: short chain dehydrogenase
Structure domains:
Length: 319 amino acids
Theoretical weight: 34.82 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P97852 (Residues: 1-319; Coverage: 43%)
Sequence domains: short chain dehydrogenase
Structure domains:
