› 1h3q

X-ray diffraction
2.4Å resolution

Crystal structure of SEDL at 2.4 Angstroms resolution

Released:
DOI: 10.2210/pdb1h3q/pdb
PDB entry 1h3q coloured by chain, front view.
PDB entry 1h3q coloured by chain, side view.
PDB entry 1h3q coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Crystal structure of SEDL and its implications for a genetic disease spondyloepiphyseal dysplasia tarda.
Jang SB, Kim YG, Cho YS, Suh PG, Kim KH, Oh BH
J Biol Chem 277 49863-9 (2002)
PMID: 12361953

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190002 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Trafficking protein particle complex subunit 2 Chain: A
Molecule details ›
Chain: A
Length: 140 amino acids
Theoretical weight: 16.46 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9CQP2 (Residues: 1-140; Coverage: 100%)
Gene names: Sedl, Trappc2
Sequence domains: Sedlin, N-terminal conserved region
Structure domains: Beta-Lactamase

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 6B
Spacegroup: C2221
Unit cell:
a: 46.69Å b: 101.3Å c: 66.15Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.213 0.213 0.248
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

13 review citations

SNAREs and traffic.
Hong W. (2005)
12 more

5 mentions without citation

The planar cell polarity effector Fuz is essential for targeted membrane trafficking, ciliogenesis and mouse embryonic development.
Gray et al. (2009)
4 more