Function and Biology Details
Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-169443 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Cyclin-dependent kinase 5
Molecule details ›
Chains: A, B
Length: 292 amino acids
Theoretical weight: 33.36 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: Protein kinase domain
Structure domains:
Length: 292 amino acids
Theoretical weight: 33.36 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
Q00535 (Residues: 1-292; Coverage: 100%)
Sequence domains: Protein kinase domain
Structure domains:
Cyclin-dependent kinase 5 activator 1, p25
Molecule details ›
Chains: D, E
Length: 147 amino acids
Theoretical weight: 17.02 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: Cyclin-dependent kinase 5 activator protein
Structure domains: Cyclin-like
Length: 147 amino acids
Theoretical weight: 17.02 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical: Q15078 (Residues: 147-293; Coverage: 48%)
Sequence domains: Cyclin-dependent kinase 5 activator protein
Structure domains: Cyclin-like
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
EMBL/DESY, HAMBURG BEAMLINE BW7A
Spacegroup:
C2
Expression system: Spodoptera frugiperda
