› 1h5p

Solution NMR

Solution structure of the human Sp100b SAND domain by heteronuclear NMR.

Released:
DOI: 10.2210/pdb1h5p/pdb
PDB entry 1h5p coloured by chain, ensemble of 10 models, front view.
PDB entry 1h5p coloured by chain, ensemble of 10 models, side view.
PDB entry 1h5p coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Primary publication:
The SAND domain structure defines a novel DNA-binding fold in transcriptional regulation.
Bottomley MJ, Collard MW, Huggenvik JI, Liu Z, Gibson TJ, Sattler M
Nat Struct Biol 8 626-33 (2001)
PMID: 11427895

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149985 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nuclear autoantigen Sp-100 Chain: A
Molecule details ›
Chain: A
Length: 95 amino acids
Theoretical weight: 11.05 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P23497 (Residues: 595-684; Coverage: 10%)
Gene name: SP100
Sequence domains: SAND domain
Structure domains: SAND domain-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: ARIA AMBIGUOUS DISTANCE RESTRAINTS SIMULATED ANNEALING WITH TORSION ANGLE DYNAMICS
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

42 review citations

Aire.
Mathis et al. (2009)
41 more

8 mentions without citation

The PWWP domain of mammalian DNA methyltransferase Dnmt3b defines a new family of DNA-binding folds.
Qiu et al. (2002)
7 more