› 1hbh

X-ray diffraction
2.2Å resolution

STRUCTURE OF DEOXYHAEMOGLOBIN OF THE ANTARCTIC FISH PAGOTHENIA BERNACCHII AND STRUCTURAL BASIS OF THE ROOT EFFECT

Released:
DOI: 10.2210/pdb1hbh/pdb
PDB entry 1hbh coloured by chain, front view.
PDB entry 1hbh coloured by chain, side view.
PDB entry 1hbh coloured by chain, top view.
Source organism: Trematomus bernacchii
Primary publication:
Structure of deoxyhaemoglobin of the antarctic fish Pagothenia bernacchii with an analysis of the structural basis of the root effect by comparison of the liganded and unliganded haemoglobin structures.
Ito N, Komiyama NH, Fermi G
J Mol Biol 250 648-58 (1995)
PMID: 7623382

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160338 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Hemoglobin subunit alpha Chains: A, C
Molecule details ›
Chains: A, C
Length: 143 amino acids
Theoretical weight: 15.68 KDa
Source organism: Trematomus bernacchii
Expression system: Not provided
UniProt:
  • Canonical: P80043 (Residues: 1-142; Coverage: 100%)
Gene name: hba
Sequence domains: Globin
Structure domains: Globins
Hemoglobin subunit beta Chains: B, D
Molecule details ›
Chains: B, D
Length: 146 amino acids
Theoretical weight: 16.15 KDa
Source organism: Trematomus bernacchii
Expression system: Not provided
UniProt:
  • Canonical: P80044 (Residues: 2-147; Coverage: 99%)
Gene name: hbb
Sequence domains: Globin
Structure domains: Globins

Ligands and Environments

1 bound ligand:
Ligand HEM 4 x HEM
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P21
Unit cell:
a: 62.65Å b: 96.3Å c: 62.65Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.16 0.16 0.22
Expression system: Not provided

Quick links

Citations

6 review citations

Functional adaptation and its molecular basis in vertebrate hemoglobins, neuroglobins and cytoglobins.
Weber et al. (2004)
5 more

12 mentions without citation

The crystal structure of a tetrameric hemoglobin in a partial hemichrome state.
Riccio et al. (2002)
11 more