› 1hcv

X-ray diffraction
1.85Å resolution

LLAMA HEAVY CHAIN VARIABLE DOMAIN AGAINST ALPHA SUBUNIT OF HCG (HUMAN CHORIONIC GONADOTROPIN)

Released:
DOI: 10.2210/pdb1hcv/pdb
PDB entry 1hcv coloured by chain, front view.
PDB entry 1hcv coloured by chain, side view.
PDB entry 1hcv coloured by chain, top view.
Source organism: Lama glama
Primary publication:
The crystal structure of a llama heavy chain variable domain.
Spinelli S, Frenken L, Bourgeois D, de Ron L, Bos W, Verrips T, Anguille C, Cambillau C, Tegoni M
Nat Struct Biol 3 752-7 (1996)
PMID: 8784347

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-213015 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
IMMUNOGLOBULIN G Chain: A
Molecule details ›
Chain: A
Length: 117 amino acids
Theoretical weight: 12.51 KDa
Source organism: Lama glama
Expression system: Saccharomyces cerevisiae
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-D
Spacegroup: P21
Unit cell:
a: 29.62Å b: 41.83Å c: 38.52Å
α: 90° β: 95.45° γ: 90°
R-values:
R R work R free
0.171 0.171 0.218
Expression system: Saccharomyces cerevisiae

Quick links

Citations

21 review citations

Properties, production, and applications of camelid single-domain antibody fragments.
Harmsen et al. (2007)
20 more

14 mentions without citation

50 Years of structural immunology.
Wilson et al. (2021)
13 more