› 1hm6

X-ray diffraction
1.8Å resolution

X-RAY STRUCTURE OF FULL-LENGTH ANNEXIN 1

Released:
DOI: 10.2210/pdb1hm6/pdb
PDB entry 1hm6 coloured by chain, front view.
PDB entry 1hm6 coloured by chain, side view.
PDB entry 1hm6 coloured by chain, top view.
Source organism: Sus scrofa
Primary publication:
X-ray structure of full-length annexin 1 and implications for membrane aggregation.
Rosengarth A, Gerke V, Luecke H
J Mol Biol 306 489-98 (2001)
PMID: 11178908

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148669 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Annexin A1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 346 amino acids
Theoretical weight: 38.8 KDa
Source organism: Sus scrofa
Expression system: Escherichia coli
UniProt:
  • Canonical: P19619 (Residues: 1-346; Coverage: 100%)
Gene names: ANX1, ANXA1
Sequence domains: Annexin
Structure domains: Annexin

Ligands and Environments

1 bound ligand:
Ligand SO4 12 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P212121
Unit cell:
a: 63.644Å b: 96.327Å c: 127.35Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.224 0.224 0.259
Expression system: Escherichia coli

Quick links

Citations

25 review citations

Annexins: from structure to function.
Gerke et al. (2002)
24 more

14 mentions without citation

Annexin-phospholipid interactions. Functional implications.
Lizarbe et al. (2013)
13 more