› 1hmk

X-ray diffraction
2Å resolution

Function and Biology Details

Reaction catalysed: 
UDP-alpha-D-galactose + D-glucose = UDP + lactose
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132936 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alpha-lactalbumin Chain: A
Molecule details ›
Chain: A
Length: 124 amino acids
Theoretical weight: 14.34 KDa
Source organism: Capra hircus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P00712 (Residues: 20-142; Coverage: 100%)
Gene name: LALBA
Sequence domains: C-type lysozyme/alpha-lactalbumin family
Structure domains: Lysozyme

Ligands and Environments

1 bound ligand:
Ligand CA 1 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MACSCIENCE M18X
Spacegroup: P21212
Unit cell:
a: 44.85Å b: 88.94Å c: 32.16Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.198 0.198 0.275
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

5 review citations

Select what you need: a comparative evaluation of the advantages and limitations of frequently used expression systems for foreign genes.
Yin et al. (2007)
4 more

1 mention without citation

TopologyNet: Topology based deep convolutional and multi-task neural networks for biomolecular property predictions.
Cang et al. (2017)