Function and Biology Details
Reaction catalysed:
L-histidine = histamine + CO(2)
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero dodecamer (preferred)
Assembly name:
Histidine decarboxylase alpha chain (preferred)
PDBe Complex ID:
PDB-CPX-133646 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Histidine decarboxylase beta chain
Molecule details ›
Chains: A, C
Length: 81 amino acids
Theoretical weight: 8.85 KDa
Source organism: Lactobacillus sp. 30A
Expression system: Escherichia coli
UniProt:
Structure domains: Pyruvoyl-Dependent Histidine Decarboxylas, subunit A
Length: 81 amino acids
Theoretical weight: 8.85 KDa
Source organism: Lactobacillus sp. 30A
Expression system: Escherichia coli
UniProt:
- Canonical:
P00862 (Residues: 2-82; Coverage: 26%)
Structure domains: Pyruvoyl-Dependent Histidine Decarboxylas, subunit A
Histidine decarboxylase alpha chain
Molecule details ›
Chains: B, D
Length: 229 amino acids
Theoretical weight: 25.29 KDa
Source organism: Lactobacillus sp. 30A
Expression system: Escherichia coli
UniProt:
Sequence domains: Histidine carboxylase PI chain
Structure domains: Pyruvoyl-Dependent Histidine Decarboxylase, subunit B
Length: 229 amino acids
Theoretical weight: 25.29 KDa
Source organism: Lactobacillus sp. 30A
Expression system: Escherichia coli
UniProt:
- Canonical: P00862 (Residues: 84-311; Coverage: 73%)
Sequence domains: Histidine carboxylase PI chain
Structure domains: Pyruvoyl-Dependent Histidine Decarboxylase, subunit B
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
RIGAKU RU200
Spacegroup:
R32
Expression system: Escherichia coli
