› 1hst

X-ray diffraction
2.6Å resolution

CRYSTAL STRUCTURE OF GLOBULAR DOMAIN OF HISTONE H5 AND ITS IMPLICATIONS FOR NUCLEOSOME BINDING

Released:
DOI: 10.2210/pdb1hst/pdb
PDB entry 1hst coloured by chain, front view.
PDB entry 1hst coloured by chain, side view.
PDB entry 1hst coloured by chain, top view.
Source organism: Gallus gallus
Primary publication:
Crystal structure of globular domain of histone H5 and its implications for nucleosome binding.
Ramakrishnan V, Finch JT, Graziano V, Lee PL, Sweet RM
Nature 362 219-23 (1993)
PMID: 8384699

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-135432 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Histone H5 Chains: A, B
Molecule details ›
Chains: A, B
Length: 90 amino acids
Theoretical weight: 9.79 KDa
Source organism: Gallus gallus
Expression system: Not provided
UniProt:
  • Canonical: P02259 (Residues: 20-109; Coverage: 47%)
Sequence domains: linker histone H1 and H5 family
Structure domains: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P21212
Unit cell:
a: 68.5Å b: 80.4Å c: 38.9Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.27 0.27 not available
Expression system: Not provided

Quick links

Citations

109 review citations

Pioneer transcription factors: establishing competence for gene expression.
Zaret et al. (2011)
108 more

34 mentions without citation

Linker histones: novel insights into structure-specific recognition of the nucleosome.
Cutter et al. (2017)
33 more