› 1hw1

X-ray diffraction
1.5Å resolution

THE FADR-DNA COMPLEX: TRANSCRIPTIONAL CONTROL OF FATTY ACID METABOLISM IN ESCHERICHIA COLI

Released:
DOI: 10.2210/pdb1hw1/pdb
PDB entry 1hw1 coloured by chain, front view.
PDB entry 1hw1 coloured by chain, side view.
PDB entry 1hw1 coloured by chain, top view.
Source organism: Escherichia coli
Primary publication:
The FadR.DNA complex. Transcriptional control of fatty acid metabolism in Escherichia coli.
Xu Y, Heath RJ, Li Z, Rock CO, White SW
J Biol Chem 276 17373-9 (2001)
PMID: 11279025

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-141750 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fatty acid metabolism regulator protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 239 amino acids
Theoretical weight: 27 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P0A8V6 (Residues: 1-239; Coverage: 100%)
Gene names: JW1176, b1187, fadR, oleR, thdB
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand SO4 6 x SO4
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P21
Unit cell:
a: 59.346Å b: 86.996Å c: 59.128Å
α: 90° β: 120.18° γ: 90°
R-values:
R R work R free
0.198 0.198 0.216
Expression system: Escherichia coli

Quick links

Citations

13 review citations

Diversity of microbial sialic acid metabolism.
Vimr et al. (2004)
12 more

10 mentions without citation

GntR Family of Bacterial Transcription Factors and Their DNA Binding Motifs: Structure, Positioning and Co-Evolution.
Suvorova et al. (2015)
9 more