› 1i3u

X-ray diffraction
1.95Å resolution

THREE-DIMENSIONAL STRUCTURE OF A LLAMA VHH DOMAIN COMPLEXED WITH THE DYE RR1

Released:
DOI: 10.2210/pdb1i3u/pdb
PDB entry 1i3u coloured by chain, front view.
PDB entry 1i3u coloured by chain, side view.
PDB entry 1i3u coloured by chain, top view.
Source organism: Lama glama
Primary publication:
Lateral recognition of a dye hapten by a llama VHH domain.
Spinelli S, Tegoni M, Frenken L, van Vliet C, Cambillau C
J Mol Biol 311 123-9 (2001)
PMID: 11469862

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-213018 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ANTIBODY VHH LAMA DOMAIN Chain: A
Molecule details ›
Chain: A
Length: 127 amino acids
Theoretical weight: 13.84 KDa
Source organism: Lama glama
Expression system: Escherichia coli
Structure domains: Immunoglobulins

Ligands and Environments

2 bound ligands:
Ligand SO4 1 x SO4
Ligand RR1 1 x RR1
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID2
Spacegroup: R32
Unit cell:
a: 77.435Å b: 77.435Å c: 175.019Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.232 0.232 0.266
Expression system: Escherichia coli

Quick links

Citations

18 review citations

Nanobodies: natural single-domain antibodies.
Muyldermans S. (2013)
17 more

8 mentions without citation

Structure and development of single domain antibodies as modules for therapeutics and diagnostics.
Hoey et al. (2019)
7 more