› 1i4h

X-ray diffraction
2.9Å resolution

Crystal structure of Zn2+ soaked Staphylococcal enterotoxin A mutant H187A

Released:
DOI: 10.2210/pdb1i4h/pdb
PDB entry 1i4h coloured by chain, front view.
PDB entry 1i4h coloured by chain, side view.
PDB entry 1i4h coloured by chain, top view.
Source organism: Staphylococcus aureus
Primary publication:
Cooperative zinc binding in a staphylococcal enterotoxin A mutant mimics the SEA-MHC class II interaction.
Håkansson M, Antonsson P, Björk P, Svensson LA
J Biol Inorg Chem 6 757-62 (2001)
PMID: 11713682

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140942 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Enterotoxin type A Chains: A, B
Molecule details ›
Chains: A, B
Length: 233 amino acids
Theoretical weight: 27.06 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli
UniProt:
  • Canonical: P0A0L2 (Residues: 25-257; Coverage: 100%)
Gene name: entA
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P212121
Unit cell:
a: 74.11Å b: 85.06Å c: 86.54Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.208 0.208 0.281
Expression system: Escherichia coli

Quick links

Citations

2 citation in other articles

Hydration of protein-protein interfaces.
Rodier et al. (2005)
1 more

1 mention without citation

The Search for Herbal Antibiotics: An In-Silico Investigation of Antibacterial Phytochemicals.
Snow Setzer et al. (2016)