1iak

X-ray diffraction
1.9Å resolution

HISTOCOMPATIBILITY ANTIGEN I-AK

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-135370 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
H-2 class II histocompatibility antigen, A-K alpha chain Chain: A
Molecule details ›
Chain: A
Length: 199 amino acids
Theoretical weight: 22.69 KDa
Source organism: Mus musculus
Expression system: CHO CELLS AS GPI-LINKED PROTEIN
UniProt:
  • Canonical: P01910 (Residues: 24-222; Coverage: 85%)
Gene name: H2-Aa
Sequence domains:
Structure domains:
H-2 class II histocompatibility antigen, A-K beta chain Chain: B
Molecule details ›
Chain: B
Length: 185 amino acids
Theoretical weight: 21.89 KDa
Source organism: Mus musculus
Expression system: CHO CELLS AS GPI-LINKED PROTEIN
UniProt:
  • Canonical: P06343 (Residues: 34-216; Coverage: 78%)
Gene name: H2-Ab1
Sequence domains:
Structure domains:
Lysozyme Chain: P
Molecule details ›
Chain: P
Length: 13 amino acids
Theoretical weight: 1.55 KDa
Source organism: Mus musculus
Expression system: CHO CELLS AS GPI-LINKED PROTEIN
UniProt:
  • Canonical: Q29431 (Residues: 18-30; Coverage: 43%)
Sequence domains: C-type lysozyme/alpha-lactalbumin family

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4A
Spacegroup: P41212
Unit cell:
a: 112.25Å b: 112.25Å c: 99.72Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.214 0.214 0.263
Expression system: CHO CELLS AS GPI-LINKED PROTEIN