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X-ray diffraction
2Å resolution

X-RAY STRUCTURE ANALYSIS OF THE IRON-DEPENDENT SUPEROXIDE DISMUTASE FROM MYCOBACTERIUM TUBERCULOSIS AT 2.0 ANGSTROMS RESOLUTIONS REVEALS NOVEL DIMER-DIMER INTERACTIONS

Released:
DOI: 10.2210/pdb1ids/pdb
PDB entry 1ids coloured by chain, front view.
PDB entry 1ids coloured by chain, side view.
PDB entry 1ids coloured by chain, top view.
Source organism: Mycobacterium tuberculosis
Primary publication:
X-ray structure analysis of the iron-dependent superoxide dismutase from Mycobacterium tuberculosis at 2.0 Angstroms resolution reveals novel dimer-dimer interactions.
Cooper JB, McIntyre K, Badasso MO, Wood SP, Zhang Y, Garbe TR, Young D
J Mol Biol 246 531-44 (1995)
PMID: 7877174

Function and Biology Details

Reaction catalysed: 
2 superoxide + 2 H(+) = O(2) + H(2)O(2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-161470 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Superoxide dismutase [Fe] Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 207 amino acids
Theoretical weight: 23.06 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Not provided
UniProt:
  • Canonical: P9WGE7 (Residues: 1-207; Coverage: 100%)
Gene names: MTCY01A6.22c, Rv3846, sod, sodA, sodB
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand FE 4 x FE
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P21
Unit cell:
a: 68.65Å b: 85.4Å c: 66.35Å
α: 90° β: 99.86° γ: 90°
R-values:
R R work R free
0.167 not available not available
Expression system: Not provided

Quick links

Citations

5 review citations

Superoxide dismutases and superoxide reductases.
Sheng et al. (2014)
4 more

8 mentions without citation

Protein unfolding: rigidity lost.
Rader et al. (2002)
7 more