› 1ie5

Solution NMR

NMR STRUCTURE OF THE THIRD IMMUNOGLOBULIN DOMAIN FROM THE NEURAL CELL ADHESION MOLECULE.

Released:
DOI: 10.2210/pdb1ie5/pdb
PDB entry 1ie5 coloured by chain, ensemble of 20 models, front view.
PDB entry 1ie5 coloured by chain, ensemble of 20 models, side view.
PDB entry 1ie5 coloured by chain, ensemble of 20 models, top view.
Source organism: Gallus gallus
Primary publication:
Solution structure of the third immunoglobulin domain of the neural cell adhesion molecule N-CAM: can solution studies define the mechanism of homophilic binding?
Atkins AR, Chung J, Deechongkit S, Little EB, Edelman GM, Wright PE, Cunningham BA, Dyson HJ
J Mol Biol 311 161-72 (2001)
PMID: 11469865

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146664 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neural cell adhesion molecule 1 Chain: A
Molecule details ›
Chain: A
Length: 107 amino acids
Theoretical weight: 11.85 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P13590 (Residues: 202-307; Coverage: 10%)
Gene name: NCAM1
Sequence domains: Immunoglobulin I-set domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing restrained molecular dynamics
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

3 review citations

Structural biology of NCAM homophilic binding and activation of FGFR.
Kiselyov et al. (2005)
2 more

2 mentions without citation

Immunoglobulin superfamily virus receptors and the evolution of adaptive immunity.
Dermody et al. (2009)
1 more