› 1ifg

X-ray diffraction
2Å resolution

CRYSTAL STRUCTURE OF A MONOMERIC FORM OF GENERAL PROTEASE INHIBITOR, ECOTIN IN ABSENCE OF A PROTEASE

Released:
DOI: 10.2210/pdb1ifg/pdb
PDB entry 1ifg coloured by chain, front view.
PDB entry 1ifg coloured by chain, side view.
PDB entry 1ifg coloured by chain, top view.
Source organism: Escherichia coli
Primary publication:
The role of ecotin dimerization in protease inhibition.
Eggers CT, Wang SX, Fletterick RJ, Craik CS
J Mol Biol 308 975-91 (2001)
PMID: 11352586

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150066 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ecotin Chain: A
Molecule details ›
Chain: A
Length: 140 amino acids
Theoretical weight: 15.85 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P23827 (Residues: 26-150, 151-162; Coverage: 97%)
Gene names: JW2197, b2209, eco, eti
Sequence domains: Ecotin
Structure domains: Ecotin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-1
Spacegroup: P43212
Unit cell:
a: 97.235Å b: 97.235Å c: 37.233Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.248 0.248 0.267
Expression system: Escherichia coli

Quick links

Citations

5 review citations

A new generation of protein display scaffolds for molecular recognition.
Hosse et al. (2006)
4 more

1 mention without citation

Protein-protein docking benchmark version 3.0.
Hwang et al. (2008)