› 1io0

X-ray diffraction
1.45Å resolution

CRYSTAL STRUCTURE OF TROPOMODULIN C-TERMINAL HALF

Released:
DOI: 10.2210/pdb1io0/pdb
PDB entry 1io0 coloured by chain, front view.
PDB entry 1io0 coloured by chain, side view.
PDB entry 1io0 coloured by chain, top view.
Source organism: Gallus gallus
Primary publication:
Crystal structure of the C-terminal half of tropomodulin and structural basis of actin filament pointed-end capping.
Krieger I, Kostyukova A, Yamashita A, Nitanai Y, Maéda Y
Biophys J 83 2716-25 (2002)
PMID: 12414704

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190106 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tropomodulin Chain: A
Molecule details ›
Chain: A
Length: 185 amino acids
Theoretical weight: 20.65 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9DEA6 (Residues: 146-330; Coverage: 54%)
Gene name: E-Tmod
Structure domains: Ribonuclease Inhibitor

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL44B2
Spacegroup: R3
Unit cell:
a: 69.294Å b: 69.294Å c: 101.223Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.203 0.203 0.22
Expression system: Escherichia coli

Quick links

Citations

13 review citations

Actin filament nucleation and elongation factors--structure-function relationships.
Dominguez R. (2009)
12 more

9 mentions without citation

Role of intrinsic disorder in muscle sarcomeres.
Tolkatchev et al. (2019)
8 more