Function and Biology Details
Reaction catalysed:
ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Lysine-tRNA ligase
- Rossmann-like alpha/beta/alpha sandwich fold
- Aminoacyl-tRNA synthetase, class I, anticodon-binding
- Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2
- Aminoacyl-tRNA synthetase, class I, anticodon-binding superfamily
- Lysine tRNA ligase, stem contact fold domain
- Aminoacyl-tRNA synthetase, class I, conserved site
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Lysine--tRNA ligase (preferred)
PDBe Complex ID:
PDB-CPX-129645 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lysine--tRNA ligase
Molecule details ›
Chains: A, B
Length: 523 amino acids
Theoretical weight: 61.66 KDa
Source organism: Pyrococcus horikoshii
Expression system: Escherichia coli
UniProt:
Sequence domains:
Structure domains:
Length: 523 amino acids
Theoretical weight: 61.66 KDa
Source organism: Pyrococcus horikoshii
Expression system: Escherichia coli
UniProt:
- Canonical:
O57963 (Residues: 1-523; Coverage: 100%)
Sequence domains:
Structure domains:
