› 1iub

X-ray diffraction
2.31Å resolution

Fucose-specific lectin from Aleuria aurantia (Hg-derivative form)

Released:
DOI: 10.2210/pdb1iub/pdb
PDB entry 1iub coloured by chain, front view.
PDB entry 1iub coloured by chain, side view.
PDB entry 1iub coloured by chain, top view.
Source organism: Aleuria aurantia
Primary publication:
Crystal structure of fucose-specific lectin from Aleuria aurantia binding ligands at three of its five sugar recognition sites.
Fujihashi M, Peapus DH, Kamiya N, Nagata Y, Miki K
Biochemistry 42 11093-9 (2003)
PMID: 14503859

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148469 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fucose-specific lectin Chain: A
Molecule details ›
Chain: A
Length: 312 amino acids
Theoretical weight: 33.43 KDa
Source organism: Aleuria aurantia
Expression system: Escherichia coli
UniProt:
  • Canonical: P18891 (Residues: 2-313; Coverage: 100%)
Sequence domains: Fungal fucose-specific lectin
Structure domains: Fucose-specific lectin

Ligands and Environments

4 bound ligands:
Ligand FUL 2 x FUL
Ligand SO4 1 x SO4
Ligand CL 2 x CL
Ligand HG 2 x HG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: P6522
Unit cell:
a: 83.909Å b: 83.909Å c: 254.131Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.156 0.156 0.183
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Entomotoxic and nematotoxic lectins and protease inhibitors from fungal fruiting bodies.
Sabotič et al. (2016)
2 more

3 mentions without citation

Mushroom lectins: specificity, structure and bioactivity relevant to human disease.
Hassan et al. (2015)
2 more