› 1iyr

Solution NMR

NMR Structure Ensemble Of Dff-C Domain

Released:
DOI: 10.2210/pdb1iyr/pdb
PDB entry 1iyr coloured by chain, ensemble of 10 models, front view.
PDB entry 1iyr coloured by chain, ensemble of 10 models, side view.
PDB entry 1iyr coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of the DFF-C domain of DFF45/ICAD. A structural basis for the regulation of apoptotic DNA fragmentation.
Fukushima K, Kikuchi J, Koshiba S, Kigawa T, Kuroda Y, Yokoyama S
J Mol Biol 321 317-27 (2002)
PMID: 12144788

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126224 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA fragmentation factor subunit alpha Chain: A
Molecule details ›
Chain: A
Length: 111 amino acids
Theoretical weight: 12.14 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O00273 (Residues: 225-331; Coverage: 32%)
Gene names: DFF1, DFF45, DFFA, H13
Structure domains: C-terminal domain of DFF45/ICAD (DFF-C domain)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Escherichia coli

Quick links

Citations

3 review citations

The protein structures that shape caspase activity, specificity, activation and inhibition.
Fuentes-Prior et al. (2004)
2 more

2 mentions without citation

Highly precise protein-protein interaction prediction based on consensus between template-based and de novo docking methods.
Ohue et al. (2013)
1 more