› 1iz9

X-ray diffraction
2Å resolution

Crystal Structure of Malate Dehydrogenase from Thermus thermophilus HB8

Released:
DOI: 10.2210/pdb1iz9/pdb
PDB entry 1iz9 coloured by chain, front view.
PDB entry 1iz9 coloured by chain, side view.
PDB entry 1iz9 coloured by chain, top view.
Source organism: Thermus thermophilus
Entry authors: Hirose R, Hasegawa T, Yamano A, Kuramitsu S, Hamada K, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
(S)-malate + NAD(+) = oxaloacetate + NADH
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145339 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Malate dehydrogenase Chains: A, B
Molecule details ›
Chains: A, B
Length: 327 amino acids
Theoretical weight: 35.47 KDa
Source organism: Thermus thermophilus
Expression system: Escherichia coli
UniProt:
  • Canonical: P10584 (Residues: 1-327; Coverage: 100%)
Gene name: mdh
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007
Spacegroup: P212121
Unit cell:
a: 71.64Å b: 88.03Å c: 118.68Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.193 0.193 0.226
Expression system: Escherichia coli

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