› 1j6r

X-ray diffraction
2.3Å resolution

Crystal structure of Activation (AdoMet binding) domain of Methionine synthase (TM0269) from Thermotoga maritima at 2.2 A resolution

Released:
DOI: 10.2210/pdb1j6r/pdb
PDB entry 1j6r coloured by chain, front view.
PDB entry 1j6r coloured by chain, side view.
PDB entry 1j6r coloured by chain, top view.
Source organism: Thermotoga maritima
Entry author: Joint Center for Structural Genomics (JCSG)

Function and Biology Details

Reaction catalysed: 
5-methyltetrahydrofolate + L-homocysteine = tetrahydrofolate + L-methionine
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194490 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Methionine synthase Chains: A, B
Molecule details ›
Chains: A, B
Length: 214 amino acids
Theoretical weight: 24.38 KDa
Source organism: Thermotoga maritima
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9WYA6 (Residues: 1-202; Coverage: 100%)
Gene name: TM_0269
Structure domains: NADH Oxidase

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: C2
Unit cell:
a: 119.396Å b: 60.74Å c: 81.574Å
α: 90° β: 99.97° γ: 90°
R-values:
R R work R free
0.251 0.251 0.29
Expression system: Escherichia coli

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