› 1jbj

Solution NMR

CD3 Epsilon and gamma Ectodomain Fragment Complex in Single-Chain Construct

Released:
DOI: 10.2210/pdb1jbj/pdb
PDB entry 1jbj coloured by chain, ensemble of 18 models, front view.
PDB entry 1jbj coloured by chain, ensemble of 18 models, side view.
PDB entry 1jbj coloured by chain, ensemble of 18 models, top view.
Source organism: Mus musculus
Primary publication:
Mechanisms contributing to T cell receptor signaling and assembly revealed by the solution structure of an ectodomain fragment of the CD3 epsilon gamma heterodimer.
Sun ZJ, Kim KS, Wagner G, Reinherz EL
Cell 105 913-23 (2001)
PMID: 11439187

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146007 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
T-cell surface glycoprotein CD3 epsilon chain; T-cell surface glycoprotein CD3 gamma chain Chain: A
Molecule details ›
Chain: A
Length: 186 amino acids
Theoretical weight: 20.63 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P22646 (Residues: 22-100; Coverage: 47%)
  • Canonical: P11942 (Residues: 22-103; Coverage: 51%)
Gene names: Cd3e, Cd3g
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

38 review citations

T cell activation.
Smith-Garvin et al. (2009)
37 more

12 mentions without citation

The structural basis of αβ T-lineage immune recognition: TCR docking topologies, mechanotransduction, and co-receptor function.
Wang et al. (2012)
11 more