› 1jd8

Solution NMR

Solution structure of lactam analogue DapD of HIV gp41 600-612 loop

Released:
DOI: 10.2210/pdb1jd8/pdb
PDB entry 1jd8 coloured by chain, ensemble of 20 models, front view.
PDB entry 1jd8 coloured by chain, ensemble of 20 models, side view.
PDB entry 1jd8 coloured by chain, ensemble of 20 models, top view.
Source organism: Human immunodeficiency virus 1
Primary publication:
Structural and immunological characterisation of heteroclitic peptide analogues corresponding to the 600-612 region of the HIV envelope gp41 glycoprotein.
Du AP, Limal D, Semetey V, Dali H, Jolivet M, Desgranges C, Cung MT, Briand JP, Petit MC, Muller S
J Mol Biol 323 503-21 (2002)
PMID: 12381305

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136945 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transmembrane protein gp41 Chain: A
Molecule details ›
Chain: A
Length: 14 amino acids
Theoretical weight: 1.37 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Not provided
UniProt:
  • Canonical: P03377 (Residues: 600-612; Coverage: 2%)
Gene name: env

Ligands and Environments

No bound ligands
1 modified residue:
Ligand DPP 1 x DPP

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion dynamics, molecular dynamics, energy minimization
Expression system: Not provided

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Citations

1 review citation

More than one reason to rethink the use of peptides in vaccine design.
Purcell et al. (2007)
11 other articles