› 1jdk

Solution NMR

solution structure of lactam analogue (EDap) of HIV gp41 600-612 loop.

Released:
DOI: 10.2210/pdb1jdk/pdb
PDB entry 1jdk coloured by chain, ensemble of 25 models, front view.
PDB entry 1jdk coloured by chain, ensemble of 25 models, side view.
PDB entry 1jdk coloured by chain, ensemble of 25 models, top view.
Source organism: Synthetic construct
Primary publication:
Structural and immunological characterisation of heteroclitic peptide analogues corresponding to the 600-612 region of the HIV envelope gp41 glycoprotein.
Du AP, Limal D, Semetey V, Dali H, Jolivet M, Desgranges C, Cung MT, Briand JP, Petit MC, Muller S
J Mol Biol 323 503-21 (2002)
PMID: 12381305

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-162259 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ACETYL GROUP Chain: A
Molecule details ›
Chain: A
Length: 14 amino acids
Theoretical weight: 1.4 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
1 modified residue:
Ligand DAB 1 x DAB

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics, energy minimization, molecular dynamics
Expression system: Not provided

Quick links

Citations

1 review citation

More than one reason to rethink the use of peptides in vaccine design.
Purcell et al. (2007)
11 other articles