› 1jes

X-ray diffraction
1.5Å resolution

Crystal Structure of a Copper-Mediated Base Pair in DNA

Released:
DOI: 10.2210/pdb1jes/pdb
PDB entry 1jes coloured by chain, front view.
PDB entry 1jes coloured by chain, side view.
PDB entry 1jes coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Structure of a copper-mediated base pair in DNA.
Atwell S, Meggers E, Spraggon G, Schultz PG
J Am Chem Soc 123 12364-7 (2001)
PMID: 11734038

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-113999 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
5'-D(*CP*GP*CP*GP*(DPY)P*AP*TP*(DRP)P*CP*GP*CP*G)-3' Chains: A, B
Molecule details ›
Chains: A, B
Length: 12 nucleotides
Theoretical weight: 3.65 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand CU 2 x CU
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P21
Unit cell:
a: 25.343Å b: 34.359Å c: 31.093Å
α: 90° β: 101.13° γ: 90°
R-values:
R R work R free
0.169 0.169 0.202
Expression system: Not provided

Quick links

Citations

10 review citations

Binding of metal ions by pyrimidine base pairs in DNA duplexes.
Ono et al. (2011)
9 more

2 mentions without citation

Chiral Systems Made from DNA.
Winogradoff et al. (2021)
1 more