› 1jff

Electron crystallography
3.5Å resolution

Refined structure of alpha-beta tubulin from zinc-induced sheets stabilized with taxol

Released:
DOI: 10.2210/pdb1jff/pdb
PDB entry 1jff coloured by chain, front view.
PDB entry 1jff coloured by chain, side view.
PDB entry 1jff coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Refined structure of alpha beta-tubulin at 3.5 A resolution.
Löwe J, Li H, Downing KH, Nogales E
J Mol Biol 313 1045-57 (2001)
PMID: 11700061

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160590 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Tubulin alpha-1B chain Chain: A
Molecule details ›
Chain: A
Length: 451 amino acids
Theoretical weight: 50.11 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P81947 (Residues: 1-451; Coverage: 100%)
Sequence domains:
Structure domains:
Tubulin beta-2B chain Chain: B
Molecule details ›
Chain: B
Length: 445 amino acids
Theoretical weight: 49.91 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: Q6B856 (Residues: 1-445; Coverage: 100%)
Gene name: TUBB2B
Sequence domains:
Structure domains:

Ligands and Environments

5 bound ligands:
Ligand ZN 1 x ZN
Ligand MG 1 x MG
Ligand GTP 1 x GTP
Ligand GDP 1 x GDP
Ligand TA1 1 x TA1
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.5Å

Quick links

Citations

81 review citations

Reaching for high-hanging fruit in drug discovery at protein-protein interfaces.
Wells et al. (2007)
80 more

242 mentions without citation

Probing protein structure by amino acid-specific covalent labeling and mass spectrometry.
Mendoza et al. (2009)
241 more