› 1jg8

X-ray diffraction
1.8Å resolution

Crystal Structure of Threonine Aldolase (Low-specificity)

Released:
DOI: 10.2210/pdb1jg8/pdb
PDB entry 1jg8 coloured by chain, front view.
PDB entry 1jg8 coloured by chain, side view.
PDB entry 1jg8 coloured by chain, top view.
Source organism: Thermotoga maritima
Entry authors: Kielkopf CL, Bonanno J, Ray S, Burley SK, New York SGX Research Center for Structural Genomics (NYSGXRC)

Function and Biology Details

Reaction catalysed: 
L-threonine = glycine + acetaldehyde
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194873 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Aromatic amino acid beta-eliminating lyase/threonine aldolase domain-containing protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 347 amino acids
Theoretical weight: 38.28 KDa
Source organism: Thermotoga maritima
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9X266 (Residues: 1-343; Coverage: 100%)
Gene name: TM_1744
Sequence domains: Beta-eliminating lyase
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand CA 6 x CA
Ligand NA 2 x NA
1 modified residue:
Ligand LLP 4 x LLP

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F2
Spacegroup: P212121
Unit cell:
a: 95.89Å b: 100.6Å c: 149.82Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.208 0.207 0.222
Expression system: Escherichia coli BL21(DE3)

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