› 1jhi

Solution NMR

Solution Structure of a Hedamycin-DNA complex

Released:
DOI: 10.2210/pdb1jhi/pdb
PDB entry 1jhi coloured by chain, ensemble of 10 models, front view.
PDB entry 1jhi coloured by chain, ensemble of 10 models, side view.
PDB entry 1jhi coloured by chain, ensemble of 10 models, top view.
Source organism: Synthetic construct
Primary publication:
Structural investigation of the hedamycin:d(ACCGGT)2 complex by NMR and restrained molecular dynamics.
Owen EA, Burley GA, Carver JA, Wickham G, Keniry MA
Biochem Biophys Res Commun 290 1602-8 (2002)
PMID: 11820806

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-114007 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
5'-D(*AP*CP*CP*(HEH)GP*GP*T)-3' Chains: A, B
Molecule details ›
Chains: A, B
Length: 6 nucleotides
Theoretical weight: 1.81 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand HEH 1 x HEH
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: Full relaxation matrix refinement Restrained Molecular Dynamics Torsion Angle dynamics
Expression system: Not provided

Quick links

Citations

3 review citations

Type II polyketide synthases: gaining a deeper insight into enzymatic teamwork.
Hertweck et al. (2007)
2 more

1 mention without citation

A comparison of the binding sites of matrix metalloproteinases and tumor necrosis factor-alpha converting enzyme: implications for selectivity.
Lukacova et al. (2005)