Function and Biology Details
Reaction catalysed:
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Histone lysine acetyltransferase CREBBP (preferred)
PDBe Complex ID:
PDB-CPX-155294 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Histone lysine acetyltransferase CREBBP
Molecule details ›
Chain: A
Length: 50 amino acids
Theoretical weight: 5.58 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
Sequence domains: Creb binding
Structure domains: Nuclear receptor coactivator, CREB-bp-like, interlocking domain
Length: 50 amino acids
Theoretical weight: 5.58 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
- Canonical:
P45481 (Residues: 2067-2112; Coverage: 2%)
Sequence domains: Creb binding
Structure domains: Nuclear receptor coactivator, CREB-bp-like, interlocking domain
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
wwPDB Validation report is not available for this NMR entry.
Refinement method:
simulated annealing
Expression system: Escherichia coli
