› 1jl5

X-ray diffraction
2.1Å resolution

Novel Molecular Architecture of YopM-a Leucine-rich Effector Protein from Yersinia pestis

Released:
DOI: 10.2210/pdb1jl5/pdb
PDB entry 1jl5 coloured by chain, front view.
PDB entry 1jl5 coloured by chain, side view.
PDB entry 1jl5 coloured by chain, top view.
Source organism: Yersinia pestis
Primary publication:
Unusual molecular architecture of the Yersinia pestis cytotoxin YopM: a leucine-rich repeat protein with the shortest repeating unit.
Evdokimov AG, Anderson DE, Routzahn KM, Waugh DS
J Mol Biol 312 807-21 (2001)
PMID: 11575934

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148169 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Outer membrane protein YopM Chain: A
Molecule details ›
Chain: A
Length: 454 amino acids
Theoretical weight: 51.59 KDa
Source organism: Yersinia pestis
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P17778 (Residues: 1-386, 387-409; Coverage: 100%)
Gene names: YPCD1.26c, YP_pCD60, y0059, y5054, yop48, yopM
Sequence domains:
Structure domains: Ribonuclease Inhibitor

Ligands and Environments

1 bound ligand:
Ligand CA 5 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X9B
Spacegroup: I4122
Unit cell:
a: 149.43Å b: 149.43Å c: 191.18Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.22 0.22 0.24
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

29 review citations

Yersinia outer proteins: role in modulation of host cell signaling responses and pathogenesis.
Viboud et al. (2005)
28 more

16 mentions without citation

Process of protein transport by the type III secretion system.
Ghosh P. (2004)
15 more