› 1jlv

X-ray diffraction
1.75Å resolution

Anopheles dirus species B glutathione S-transferases 1-3

Released:
DOI: 10.2210/pdb1jlv/pdb
PDB entry 1jlv coloured by chain, front view.
PDB entry 1jlv coloured by chain, side view.
PDB entry 1jlv coloured by chain, top view.
Source organism: Anopheles cracens
Primary publication:
The crystal structures of glutathione S-transferases isozymes 1-3 and 1-4 from Anopheles dirus species B.
Oakley AJ, Harnnoi T, Udomsinprasert R, Jirajaroenrat K, Ketterman AJ, Wilce MC
Protein Sci 10 2176-85 (2001)
PMID: 11604524

Function and Biology Details

Reaction catalysed: 
RX + glutathione = HX + R-S-glutathione
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181585 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
glutathione transferase Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 209 amino acids
Theoretical weight: 23.81 KDa
Source organism: Anopheles cracens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q7KIF2 (Residues: 1-209; Coverage: 100%)
Gene name: GST1
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand GSH 6 x GSH
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P43
Unit cell:
a: 87.81Å b: 87.81Å c: 166.1Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.223 0.223 0.231
Expression system: Escherichia coli

Quick links

Citations

6 review citations

Glutathione transferases: a structural perspective.
Oakley A. (2011)
5 more

18 mentions without citation

Control of Initiation of DNA Replication in Bacillus subtilis and Escherichia coli.
Jameson et al. (2017)
17 more