› 1jlw

X-ray diffraction
2.45Å resolution

Anopheles dirus species B glutathione S-transferases 1-4

Released:
DOI: 10.2210/pdb1jlw/pdb
PDB entry 1jlw coloured by chain, front view.
PDB entry 1jlw coloured by chain, side view.
PDB entry 1jlw coloured by chain, top view.
Source organism: Anopheles cracens
Primary publication:
The crystal structures of glutathione S-transferases isozymes 1-3 and 1-4 from Anopheles dirus species B.
Oakley AJ, Harnnoi T, Udomsinprasert R, Jirajaroenrat K, Ketterman AJ, Wilce MC
Protein Sci 10 2176-85 (2001)
PMID: 11604524

Function and Biology Details

Reaction catalysed: 
RX + glutathione = HX + R-S-glutathione
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181584 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
glutathione transferase Chains: A, B
Molecule details ›
Chains: A, B
Length: 219 amino acids
Theoretical weight: 25 KDa
Source organism: Anopheles cracens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q7KIF1 (Residues: 1-219; Coverage: 100%)
Gene name: GST1
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P3221
Unit cell:
a: 49.44Å b: 49.44Å c: 271.81Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.223 0.223 0.271
Expression system: Escherichia coli

Quick links

Citations

7 review citations

Glutathione transferases: a structural perspective.
Oakley A. (2011)
6 more

7 mentions without citation

Identification, characterization and structure of a new Delta class glutathione transferase isoenzyme.
Udomsinprasert et al. (2005)
6 more