› 1jrj

Solution NMR

Solution structure of exendin-4 in 30-vol% trifluoroethanol

Released:
DOI: 10.2210/pdb1jrj/pdb
PDB entry 1jrj coloured by chain, ensemble of 36 models, front view.
PDB entry 1jrj coloured by chain, ensemble of 36 models, side view.
PDB entry 1jrj coloured by chain, ensemble of 36 models, top view.
Source organism: Heloderma suspectum
Primary publication:
Exendin-4 and glucagon-like-peptide-1: NMR structural comparisons in the solution and micelle-associated states.
Neidigh JW, Fesinmeyer RM, Prickett KS, Andersen NH
Biochemistry 40 13188-200 (2001)
PMID: 11683627

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150707 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Exendin-4 Chain: A
Molecule details ›
Chain: A
Length: 39 amino acids
Theoretical weight: 4.19 KDa
Source organism: Heloderma suspectum
Expression system: Not provided
UniProt:
  • Canonical: P26349 (Residues: 48-86; Coverage: 61%)
Sequence domains: Peptide hormone

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Not provided

Quick links

Citations

24 review citations

Glucagon-like peptide 1 (GLP-1).
Müller et al. (2019)
23 more

16 mentions without citation

Site-Specific and Stoichiometric Stealth Polymer Conjugates of Therapeutic Peptides and Proteins.
Ozer et al. (2017)
15 more